Coagulation factor XIII A chain; Coagulation factor XIII A1 polypeptide; Coagulation factor XIIIa; F13A; F13a1; Factor XIIIA; Fibrin stabilizing factor, A subunit; 


As you have mentioned in your e-mail, dendritic cells also express Factor XIIIa. However, the expressed levels of Factor XIIIa may be different from that in the placenta which usually shows very high levels of this protein. We have looked through our order record and actually the batch number you received was 77421.

Factor XIIIa Faktor XIIIa Svensk definition. Den aktiverade formen av faktor XIII, ett transglutaminas, som stabiliserar bildandet av den fibrinpolymer (blodkrusta) som utgör slutskedet i koagulationskaskaden. Engelsk definition 1. J Cutan Pathol.

Factor xiiia

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Antonyms for Factor xiiia. 1 synonym for factor XIII: fibrinase. What are synonyms for Factor xiiia? Factor XIIIa is a blood proenzyme that has been identified in platelets, megakaryocyte, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present in monocytes and macrophages and dermal dendritic cells.

2007-01-23 · Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.

Factor xiiia synonyms, Factor xiiia pronunciation, Factor xiiia translation, English dictionary definition of Factor xiiia. Noun 1. factor XIII - in the clotting of blood thrombin catalyzes factor XIII into its active form which causes fibrin to form a stable clot fibrinase After activation of the zymogen by Thrombin and Ca2+ to its active form (a*2, Factor XIIIa), Factor XIIIa catalyzes the formation of covalent bridges (ε- (γ-glutamyl) lysine bonds) between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is insoluble and resistant to lysis.

Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII.

Factor XIII is activated by thrombin in the presence of calcium which leads to the release of the activation peptide, followed by the dissociation of carrier subunits. The activated Factor XIII (XIIIa) acts on fibrin (Factor Ia) to form γ-glutamyl-Є-lysyl amide cross links between fibrin molecules leading to the formation of an insoluble clot. Metoda – test de solubilizare a cheagului (se determina cea mai mare dilutie a plasmei la care un cheag, obtinut prin adaugarea de trombina si calciu la un fibrinogen exogen fara factor XIII, ramane insolubil in prezenta acidului cloroacetic) 4. Valori de referinta – 80% -150% 4. Limite si interferente 1 Sep 1998 We show that factor XIIIa (FXIIIa, the potentially active a2‐subunit of factor XIII), an enzyme that participates in blood coagulation by stabilizing  Factor XIIIa rapidly cross-links α2-antiplasmin to the α-chain of fibrin.67,68  Invitrogen Human Factor XIIIa Protein, Catalog # RP-43123. Tested in Control ( Ctrl) applications. Supplied as 50 µg purified protein (2.4 mg/mL).

Factor xiiia

Factor XIIIa-positive dendrocytes in malignant melanoma. Piérard-Franchimont C, Piérard GE. Comment on J Cutan Pathol. 1998 Nov;25(10):553-8. Factor XIII, also known as fibrin-stabilizing factor, is a 320-kDa glycoprotein that is the proenzyme for plasma transglutaminase. In plasma, it circulates as a proenzyme consisting of two catalytic A subunits and two noncatalytic B subunits.
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In vivo imaging of FXIIIa activity could  1 Jan 2007 It has been demonstrated recently that coagulation factor XIII (FXIII) plays an extraordinary role in myocardial healing after infarction, improving  Buy mouse monoclonal (F13A1/1448) antibody to Factor XIIIa (A248512). Applications: WB, IHC and more. Reactivity: Human. ✔️ FREE Shipping. Human Factor XIIIa.

It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system. Factor XIII deficiency is an extremely rare inherited blood disorder characterized by abnormal blood clotting that may result in abnormal bleeding. Signs and symptoms occur as the result of a deficiency in the blood clotting factor 13, which is responsible for stabilizing the formation of a blood clot. Factor XIIIa, also known as fibrinoligase and fibrin-stabilizing factor, is the last enzyme generated in the blood coagulation cascade.

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TAFI. Trombin-activable fibrinolysis inhibitor. TEG. Thrombelastography. TF. Tissue factor. TFPI. Tissue factor pathway inhibitor. TIA. Transitorisk ischemisk attack.

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Factor XIIIa can be used in a panel with D2-40 and CD34 to differentiate between DFSP (factor XIIIa-, D2-40-, CD34+) and dermatofibroma (factor XIIIa+, D2-40+, CD34-). However, exceptions occur. Factor XIIIa is a pan-histiocytic marker, similar to CD68. Common Pitfalls [edit | edit source] Not specific for dermatofibroma. References [edit

Factorul XIII sau factorul stabilizator al fibrinei este o molecula tetramerica sintetizata la nivelul hepatocitelor si megacariocitelor.